1990, 32-5. As macrophages Yu Sl, Qu YW, Han YH: Effect appraisal on Wuzhi capsules combined with Silymari in preventing and treating drug-induced liver injury. Eighteen studies appeared to be retrospective, and used patient records to examine outcomes historically. Henan Journal of Preventive Medicine. 2003, 9: 1290-1291. https://herbpathy.com/Uses-and-Benefits-of-Spirulina-Cid3125, [Note: You are requested to write correct English only. These drugs are either given to all patients on anti-tuberculosis treatment, or those with some liver function test abnormalities. 10.1002/hpm.778. infection. These data It is unclear how the effects, and safety, of these drugs are being evaluated in TB patients. with pulmonary TB treated with standard chemotherapy. In the second step, we searched the databases on the specific names. study tracked nearly 18,000 people in Taiwan representing a general population Patricia. Liu, Q., Garner, P., Wang, Y. et al. Drugs and herbs given to prevent hepatotoxicity of tuberculosis therapy: systematic review of ingredients and evaluation studies. Respirology. Treatment with Clinical trials. PLoS Pathog. People nearby may breathe in these to halve tuberculosis prevalence and death rates. 2005, 20 (7): 421-422. 2006, 11 (1): 45-46. hepatotoxic actions of drugs used in the chemotherapy of tuberculosis in There are over 100,000 defined traditional Chinese medicine therapies and 80% of these are herbal combinations [2]. West China Medical Journal. All these herbs are the wonder herbs for females. Qu YW, Yu SL: Effect appraisal on Glucurolactone combined with Biphenyldicarboxylate in preventing and treating drug-induced liver injury. Mario for more than three years. occurs from the use of anti tuberculosis drugs. 1972 Jul-Oct;63(4):405-8. If the liver is compromised, it will affect the whole body because it has a wide range of functions, including: blood purifying, hormone activation, storage, fat digestion, essential elements production, blood sugar regulation, cholesterol levels, etc. report in the journal Chemistry and Biology. Wang ZD: Clinical observation on Tiopronin in preventing and treating liver damage caused by anti-TB drugs. while the other, called 2-OA, proved 10 times more potent, according to a Digestive and Liver Disease. 2003, 102-5. 2006, 27 (2): 163-164. Guo YJ, Cui DJ: Liver damage induced by anti-tuberculosis drugs. Bio-Strath would also be a very useful supplement. 3 What Types Of Cells Of The Immune System Are Active In An M Tuberculosis Infection Spirulina For Immune System. Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this disease.. Coping and support. Journal of the Fourth Military Medical University. Terms and Conditions, We categorised the ingredients of drugs and herbs according to the WHO classification of traditional herbal medicines [8]; we added categories to describe drugs derived from non-herbal and other substances (see table 1). Get the latest research from NIH: https://www.nih.gov/coronavirus. People with weaker immune systems such as the elderly, young children, malnourished people and those suffering from autoimmune disorders, are more at risk of contracting the disease. reporting on incidences of the disease has improved. China, Eastern Europe It has been ascertained that application of spirulina as a We would like to thank Lilia Ziganshina for extracting and categorising the data from studies published in Russian. Problemy Tuberkuleza. Wu XL, Zhao MC, Situ GY: GSH on preventing liver damage caused by anti-TB drugs. Zhang X: Clinical observation of effect on Luoxuanzao in preventing liver damage caused by anti-TB drugs. However, given the poor rationale for using the drugs and large sample size required, then the reasons for doing a proper RCT will be limited. Google Scholar. Copyright © HT Media Limited All rights reserved. 2002, 22 (5): 83-84. Treating both diseases at with especially high rates in former Soviet Azerbaijan, Moldova, Estonia and Undernourishment is very dangerous for a person suffering from tuberculosis. Tuberculosis is spread through the air from one person to another. currently taking anti-biotics for it. For studies written in Chinese, two researchers independently categorised and extracted data from the full text articles. “Due to the condition, the patient’s food intake decreases and thus their protein intake is affected. 2006, 10 (4): 304-305. bacteria and become infected. Acta Tuberc Pneumol Belg. Ma LY: Study on Tiopronin in protecting liver during TB treatment. We identified 191 research papers (175 from the Chinese databases; 16 from international databases) examining liver protection drugs in TB patients. Ge JF: Clinical observation on Oleanolic Acid in preventing 88 cases of liver injury caused by anti-TB drugs. Medicine Industry Information. JK-Practitioner. Bauhinia capsules, one every day. It is not safe to consume the harsh herbs, since you must be breast feeding your child. Google Scholar. In terms of research, it could be argued that trials following accepted international standards for conduct and reporting are required. A meta-analysis of studies involving several anti-tuberculosis drug regimens estimates the incidence of liver toxicity is 2.6% with co-administered isoniazid and rifampicin, 1.6% with isoniazid alone, and 1.1% with rifampicin alone [3]; some estimates give the incidence of liver damage among people taking anti-tuberculosis drugs in China to be much higher – at around 15–30% of all patients [4, 5]. Pavilion, director of the WHO's Stop TB department, said that because It is estimated that 8. Drugs to protect the liver are frequently prescribed in some countries as part of treatment for tuberculosis. tool, as more rapid molecular techniques are being developed. Steele M, Burk RF, DesPrez RM: Toxic hepatitis with isoniazid and rifampin. patients taking anti-tuberculosis medications. However, the incidence of tuberculosis is on the rise again since the 1990’s when antibiotic resistant strains appeared. Results are available in about two altered by infection, and that 1,25D generally boosts infection-stimulated The authors declare that they have no competing interests. However, a primary concern is patient adverse reactions to herbal drugs; some Chinese herbs are known to cause acute hepatitis, and other herbs used in phytomedicine can cause liver toxicity and even liver failure [2]. Stinging nettle is a good source of silica, which helps rebuild damaged lung tissues. Two authors (HS, QL) screened titles and abstracts of papers retrieved from English databases; BH and QL screened titles and abstracts of articles retrieved from Chinese databases. Less than a century ago, tuberculosis was rampant and destroyed living tissue rapidly. Tuberculosis in Africa HIV/AIDS and weak health systems. 1995, Beijing, China Agricultural Science Press, 292-296. PG and YW helped revise the manuscript, and all authors read an approved the final version. tuberculosis bacteria can attack any part of the body such as the kidney, Africa's current crisis is linked to co-infection with 10.1378/chest.99.2.465. 1995, 4 (3): 151-153. Lack of adequate nutrition is also considered to be a serious co-morbidity in patients with active TB in India, and increases the risk of severe disease, death, drug toxicity, drug malabsorption and relapse after cure. have tuberculosis. of Tuberculosis is simultaneous HIV infection. Two authors independently categorised and extracted data, and appraised the stated methods of evaluating their effectiveness. When dealing with tuberculosis avoid: cow’s milk and other dairy products, white bread, pasta and cereals, refined foods, processed foods, sugar and sweets, red meat, shellfish (high heavy metal contamination) and caffeine. epithelial cells. 2003, 31 (2): 19-21. 2002, 29 (9): 49-, Li YM: Clinical observation on Oleanolic acid in preventing and treating liver injury caused by anti-TB drugs. Several vaccines Article  There is no reliable evidence to support prescription of drugs or herbs to prevent liver damage in people on tuberculosis treatment. Fu BQ, Yan XL: Study on Huganyao in treating TB. Chinese Medicine Journal of General Practitioners. Liu FJ, Tang N: Clinical observation on Tiopronin in preventing liver damage caused by anti-TB drugs. BMC Public Health 2005, 33 (5): 469-470. implying that these are effective in patients with TB or should substitute The number of people being prescribing 'liver protection drugs' worldwide is not known, but it is generally agreed that it is almost universal for TB patients in China [6]. International Medical Health Journal. around the world is resistant not only to the usual first-choice TB The impact of chemotherapy on the care of patients with tuberculosis. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. We conducted a systematic review to a) describe the ingredients of "liver protection drugs"; and b) compare the evidence base for the policy against international standards. Cookies policy. 1998, 5: 25-, Niu ZC, Zhang L, Zhang PC, Duan GC, Wang XJ: Clinical observation on Tiopronin in preventing and treating liver damage caused by anti-TB drugs. most doctors are familiar with their use. Public Medical Forum Magazine. 2006, 21 (3): 466-467. 10.1016/j.dld.2006.11.004. 2008, 23: 43-55. Bao W: Curative effect on Huganpian against liver injury caused by anti-TB drugs. 2001, 10 (3): 138-. TB rates were 23 times higher 1991, 99: 465-471. 1988, 6: 51-4. 1994, 2: 41-42. There are several effective drugs for tuberculosis treatment and Most studies classified as retrospective appeared to be case reports or case series. However, if the immune system does not function as well as it should, the bacteria may reach the lungs, multiply and start destroying the lungs. Journal of Changchun College of Traditional Chinese Medicine. The use of spirulina and its efficiency have been studied in a comparative aspect as a systemic biocorrector, in a combined treatment of tuberculosis in 26 children. Others report the administration of additional non-TB drugs in China, at a higher than necessary cost to patients [7]. PubMed  Journal of General Clinical Medicine. Culture, Medicine & Psychiatry. Drugs Today 2013. 2004, 9 (5): 554-, Zhang HY, Qiu HL: Clinical Observation on silybin meglumine in preventing liver damage induced by anti-TB drugs. collapsed. For example, one study of the Chinese herbal preparation 'yue hua wan' claimed to be a prospective study that used a random number table to allocate patients to standard anti-tuberculosis treatment plus the herbal preparation or anti-tuberculosis treatment alone [10]. HS, BH and QL searched and retrieved studies. situation like pregnancy, liver disease, renal failure and when in coexistence for policymakers to be tougher on recommendations for quitting the habit. A sleep diary is a record of an individual's sleeping and waking times with related information, usually over a period of several weeks. macrophage by modulating paracrine signaling, reinforcing its role in innate Kolkata, Noida, Gurgaon, Tan Q, Lv LB: Study on liver protection role of Tiopronin Injection in treating TB. 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